Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length221 amino acids

Chemical FormulaC1120H1750N270O331S10

DescriptionStandard

        TCKLQVLGMLLKLLTRNPNTSLCPEAMIWPSPFLADLAEVDYSLSGLPAVFQPFIDLDLKGIVFPAGNYTDSPYVAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTTGAVNRTIAEETCNYFNINTEIFSSIIPEVSIISFTKSQRSHPPVMLKLKSTEIPINSLQQDSFMVKIQGSVKVLVILPDSNTRSLFTLNILTNTSISLNIFDQKLMGSLCLNR
    

Molecular Weight24614.14 Da

Isoelectric Point (pI)4.95

Net Charge (pH 7.0)-4.54

Net Charge (pH 7.4) -4.88

Charge Density (pH 7.0) -0.0205

GRAVY Index0.21

Hydrophobic Moment 0.60

Boman Index0.18

Instability Index46.68

Aliphatic Index 100.14

Aromaticity 0.1086

Extinction Coeff. Reduced 17420.00

Extinction Coeff. Oxidized 17670.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341120 VERIFIED: NO

Provenance & Taxonomy

OrganismVidua chalybeata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria