Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2308H3646N628O652S11

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGIAILEKQLSQLKLSDISGESRVWRMGKVRYELSRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLFARDRGSFDLKVENVYIKINLRLGSDATGKPTVSTSECSAHISKVRVLFSGKFGWLYNLFHSTIESRFRKILEDKVCDIVDKSLHNELQTYVRTLPVTARINDKTGIDYSLVAPPRATAQSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYREAGALVFEITEDMIPKDAGFRLETSIFSAFIPQLEEMYPNMPMKFRLSTPAAPFLTIGPGGISLKPTVDAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGRMVGSVDVGRIRLSLKDSAVGTFQVRTMQSLMNILTSSTLLPRLNARLDEGFPLPLLDRIQLSNILVRFHQNFLLLGADVHFQPQ
    

Molecular Weight50976.17 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)9.30

Net Charge (pH 7.4) 8.48

Charge Density (pH 7.0) 0.0204

GRAVY Index0.00

Hydrophobic Moment 0.63

Boman Index0.06

Instability Index33.65

Aliphatic Index 99.21

Aromaticity 0.0965

Extinction Coeff. Reduced 35870.00

Extinction Coeff. Oxidized 35995.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0331529 VERIFIED: NO

Provenance & Taxonomy

OrganismMohoua ochrocephala [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria