Peptide Database

Peptide NameEsculentin 2LSa

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC171H284N50O46S3

DescriptionStandard

        GLGSIFLKGAKWLGKNMIKQVGKAGAEHLACKATNQC
    

Molecular Weight3872.59 Da

Isoelectric Point (pI)9.79

Net Charge (pH 7.0)4.82

Net Charge (pH 7.4) 4.53

Charge Density (pH 7.0) 0.1304

GRAVY Index-0.05

Hydrophobic Moment 0.66

Boman Index0.10

Instability Index0.76

Aliphatic Index 84.59

Aromaticity 0.0541

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1561.63

LogP -15.49

H-bond Donors 55.0

H-bond Acceptors 55.0

Rotatable Bonds 136.0

Heavy Atoms 270.0

Ring Count 4.0

Amide Bonds 40.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0001152 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana luctuosa [Animal]

FamilyEsculentin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli

Activity32 μM

MethodMIC

RECORD: Rec_0100684 VERIFIED: YES