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MYP_040358
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Basic Information
KEN
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Dengue virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
3 amino acids
C15H27N5O7
Standard
Sequence
KEN
Physicochemical Analysis
389.40 Da
6.00
-0.24
-0.44
-0.0794
-3.63
0.26
-1.01
6.67
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
227.93
-2.76
7.0
7.0
14.0
27.0
0.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016046 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 24612829 PMID24612829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24612829/
RECORD: Rec_0124305 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-DENV Entry inhibition
Dengue virus 2(DENV2) | Vero cells
331.9 μM
IC50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperPeptide inhibitors against dengue virus infection. | Panya A, Bangphoomi K, Choowongkomon K, Yenchitsomanus PT. | Chem Biol Drug Des. 2014 Aug;84(2):148-57. | DOI:10.1111/cbdd.12309 | PMID:24612829 PMID24612829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24612829/
RECORD: Rec_0276568 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
dengue virus 2(DENV2):inhibition of viral entry in Vero cells
331.9 μM
IC50
PaperPubMed PMID: 24612829 PMID24612829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24612829/
RECORD: Rec_0298610 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
toxicity against Vero cells up to 500 μM
500 μM
Cytotoxicity
PaperPubMed PMID: 24612829 PMID24612829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24612829/
RECORD: Rec_0399084 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 24612829 PMID24612829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24612829/