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MYP_040343
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Basic Information
Gramicidin S analog 3
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
PXVXLXFPXVXLXF
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013330 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,6,9,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 1110301981HT034-PVL+
64.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0049305 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,6,9,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
64.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0059195 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,6,9,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
32.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0095621 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,6,9,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC 29212
64.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0254051 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,6,9,11,13
Bio-Activity Profile
Hemolytic
human red blood cells
100 % hemolysis at >500 μM
Hemolysis
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
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