Peptide Database

Peptide NameDefensin alpha 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC446H727N131O138S9

DescriptionStandard

        MRIITLLAAILFVALQARAGPLQARGDEAAGQEQRGADDQDISISFAWDKSSALQVSGSTRGMVCSCRLVFCQRTELRVGNCVIGGMSFTYCCTLVD
    

Molecular Weight10420.92 Da

Isoelectric Point (pI)6.15

Net Charge (pH 7.0)-0.54

Net Charge (pH 7.4) -0.86

Charge Density (pH 7.0) -0.0056

GRAVY Index0.26

Hydrophobic Moment 0.59

Boman Index0.09

Instability Index34.44

Aliphatic Index 92.58

Aromaticity 0.0619

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4348.78

LogP -49.63

H-bond Donors 160.0

H-bond Acceptors 147.0

Rotatable Bonds 349.0

Heavy Atoms 724.0

Ring Count 8.0

Amide Bonds 104.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0054324 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence