Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length188 amino acids

Chemical FormulaC927H1487N265O274S13

DescriptionStandard

        MSKSVKVGVFVCSVAAIIGTVKQYYSSEIRTSETGLAIIGNAEGCRRDPYKCPADVITVGIGSTEASGEKINVNHKYTDKEIAERWIKDLKIAERCINRYFNGDKMNENQFSAMVSAAFNMGCYNLRFYPNENGKYIQTTIHKYAMAKDFKAMCNRIPDFNRSGGKVLRGLKIRREKEKALCLGQEVK
    

Molecular Weight21145.18 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)10.62

Net Charge (pH 7.4) 10.13

Charge Density (pH 7.0) 0.0565

GRAVY Index-0.42

Hydrophobic Moment 0.82

Boman Index-0.08

Instability Index32.14

Aliphatic Index 74.20

Aromaticity 0.0904

Extinction Coeff. Reduced 18910.00

Extinction Coeff. Oxidized 19285.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8825.16

LogP -105.85

H-bond Donors 315.0

H-bond Acceptors 300.0

Rotatable Bonds 704.0

Heavy Atoms 1479.0

Ring Count 24.0

Amide Bonds 204.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269000 VERIFIED: YES

Provenance & Taxonomy

OrganismMannheimia phage PHL101 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0422074 VERIFIED: YES