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MYP_040303
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
8 amino acids
C44H64N12O12
Standard
Sequence
PTHIKWGD
Physicochemical Analysis
953.05 Da
7.18
0.05
-0.06
0.0061
-1.21
0.29
-0.01
40.10
48.75
0.1250
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
381.05
-2.43
14.0
13.0
28.0
68.0
4.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001227 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
ACE-inhibitory peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
0.9 μM
IC50
PaperInhibition strength of short peptides derived from an ACE inhibitory peptide. PMID21923188 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21923188/
RECORD: Rec_0029011 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
1.5
IC50
PaperKohama Y., Matsumoto S., Oka H., Teramoto T., Okabe M., Mimura T.. Isolation of angiotensin-converting enzyme inhibitor from tuna muscle. Biochem. Biophys. Res. Commun., 155, 332-337.
RECORD: Rec_0052738 VERIFIED: YES
Provenance & Taxonomy
Thunnus albacares,Neothunnus macropterus [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
0.90 μM
IC50
RECORD: Rec_0199849 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
8 μM
IC50
PaperReview on the angiotensin-I-converting enzyme (ACE) inhibitor peptides from marine proteins. PMID23271625 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23271625/
RECORD: Rec_0231140 VERIFIED: YES
Provenance & Taxonomy
Neothunnus macropterus [Animal]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
1 μM
IC50
PaperIsolation of angiotensin-converting enzyme inhibitor from tuna muscle PMID3415688 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3415688/
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