Peptide Database

Peptide NameSLAY-screened peptide P3369

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC69H112N26O19S

DescriptionStandard

        RAPCSHRTGGFLPSR
    

Molecular Weight1641.86 Da

Isoelectric Point (pI)11.70

Net Charge (pH 7.0)2.84

Net Charge (pH 7.4) 2.57

Charge Density (pH 7.0) 0.1892

GRAVY Index-0.81

Hydrophobic Moment 0.31

Boman Index-0.27

Instability Index58.23

Aliphatic Index 32.67

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 728.21

LogP -10.18

H-bond Donors 28.0

H-bond Acceptors 24.0

Rotatable Bonds 49.0

Heavy Atoms 115.0

Ring Count 4.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0256049 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/