Peptide Database

Peptide NameGlucagon-36

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC183H280N54O58S

DescriptionStandard

        HSQGTFTNDYSKYLDTRRAQDFVQWLMSTKRSGGIT
    

Molecular Weight4196.57 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.0513

GRAVY Index-0.97

Hydrophobic Moment 0.66

Boman Index-0.19

Instability Index64.92

Aliphatic Index 43.33

Aromaticity 0.1389

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1870.82

LogP -23.08

H-bond Donors 68.0

H-bond Acceptors 62.0

Rotatable Bonds 139.0

Heavy Atoms 296.0

Ring Count 7.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0127314 VERIFIED: NO

Provenance & Taxonomy

OrganismLepisosteus spatula,Atractosteus spatula [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0133371 VERIFIED: YES

Provenance & Taxonomy

OrganismAtractosteus spatula [Animal]

FamilyGlucagon

Tax ID7917

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0221230 VERIFIED: YES

Provenance & Taxonomy

OrganismAtractosteus spatula [Animal]

FamilyGlucagon

Tax ID7917

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0270794 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/