MYP_040225
Alyteserin-2a [A10W, G11k, N15k]
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
▸
Cytotoxic
Antimicrobial
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
Standard
16 amino acids
C86H150N20O20
Standard
ILGKLLSTAWKLLSKL
1784.23 Da
10.30
2.76
2.55
0.1723
0.86
0.59
0.30
0.19
176.88
0.0625
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
654.36
-1.88
24.0
23.0
62.0
126.0
2.0
15.0
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0091048
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Alyteserin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
k=D-Lys
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
RECORD: Rec_0138898
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Alyteserin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
k=D-Lys
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
Human erythrocytes
68 μM
Hemolysis
RECORD: Rec_0398680
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Alyteserin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
k=D-Lys
Bio-Activity Profile
Antimicrobial
Anticancer
Tumor cells: A549
17 μM
LC50