Peptide Database

Peptide NameType VI secretion system tip protein VgrG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1198 amino acids

Chemical FormulaC5850H9145N1677O1805S31

DescriptionStandard

        MDNWSALFDGQTRYVLDINDSTVKADVLRFRGREALSEPFRWDIEFTSLHANIPPEQVLMKYASLRMRGGKNVHGMVTRLEWLSTSRDQSHYRLTLSSRLTLLGYTRQCAVFQNLSVPEVVEQVLRKHGLEGPDFEFRLERIYPARELITQWRETDLQFIQRILSEVGIYWRTEMDDVRGLDTCILADSQLNYRFDVQLPYSEPSGLFDGAADSVWDVRTWHNIATGTVATRDYNYRTATTPMDATVSVRSDAVTTGAHYRYTAPYRDAGDDTSPEPETESGAFYARIHHERELNRSARIHLFSNTAHLTPGQVLEPQGDVITALKEGVILTLVTFRGARDSRLHVSVWGVPYTERYCFRPAEIPRPLIPGTLPARIESREKNDISPHLDEQGRYRVRLDFDRDATDPGYGYLWLRMAKPTAGETSGWHTPLTDGTEVAIAYSNGDIDLPYIACALHDSEHPDHVTRDNHTRNVLRTPANNKLRMEDRRGEEHIKLATEYGKSQLNSGHLVDSKGQRRGTGAELRTDEHGVIRAGKGLFVSADAQPKAQGEALDRDAALKEIDRLNQQLQQLEIAAEKAQALKADVDSQIQMFAQRLKPLNEALLMTAPEGMALTSGEDMQLAATKNVAVNAGGDISAGVTGNLTALAGEKLGLFARSGQLSLKSGERAIDVQAQNASLRLFAEKKLTLSSASDISFAGKKRITLIGGGSYLRLEAGKVEYGTTASYMRKVKRTMAASASAKPAEAVSLPPPATMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAEEPVDNFGQMTIFAQPVEDDCCGYGHQHEHADDEVVQHAQSAKKRKPDAGGANAPAPAQATAAPLALGAATGVMTQVWGEWSLTGVLGAARGIPYVGAMMSALYVPSAGEGSDRVPGRDEFWYEEELRQKALTGAKATTRVRFFWRQDEQGNMRVYGVHTGEGTPYEGVRTANMEWNSENNRYEFTPAHGADGPLITWTPERPEGSDLPSHTGSDIRPIDQATILVTPIPDGKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKDDARNVPGEATGNGVKLSGDKPWLDMSVTNSGEGAPIPSQIADKLRGQKFNSFDDFRETIWNEIGRHPELTKDFTTVNKDRIEDGLAPWVPKEGQYIGPNSIVKKFAIHHVVPIKDGGGVYDMDNLRIVTPKLHDEIHYRR
    

Molecular Weight132842.36 Da

Isoelectric Point (pI)5.67

Net Charge (pH 7.0)-25.56

Net Charge (pH 7.4) -27.84

Charge Density (pH 7.0) -0.0213

GRAVY Index-0.52

Hydrophobic Moment 0.74

Boman Index-0.05

Instability Index33.05

Aliphatic Index 75.61

Aromaticity 0.0785

Extinction Coeff. Reduced 169600.00

Extinction Coeff. Oxidized 170100.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022157 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyColicin/Bacteriocin

Tax ID28901

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence