Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length265 amino acids

Chemical FormulaC1322H2062N340O383S7

DescriptionStandard

        QVCENVAKSVQNELQKQVRTLPVTARIDDKIGVDYSLVAPPRATSKSLDVDLKGEFYSLAHRSTIPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHKAGALVFEISEATIPNDVEFKLNTSVFSAFIPQLEEKYPNMPMKFRLSTPTAPFLTIGPGGISFQPIVDVQAYAILPNSSLAPLFLLSLVSSDTAFGNGAEGSLSCSQSPFPPPHPTPQVRTMQSLMNILTSSTLLPRLNARLDEGFPLPLLDRIQLSNILVRFHQ
    

Molecular Weight29071.02 Da

Isoelectric Point (pI)6.23

Net Charge (pH 7.0)-1.80

Net Charge (pH 7.4) -2.33

Charge Density (pH 7.0) -0.0068

GRAVY Index0.02

Hydrophobic Moment 0.62

Boman Index0.12

Instability Index43.67

Aliphatic Index 92.38

Aromaticity 0.0943

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0208568 VERIFIED: NO

Provenance & Taxonomy

OrganismLoxia leucoptera [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria