Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC428H713N121O120S12

DescriptionStandard

        MKLLFLFLAILLAMEPVMSGECWMDGRCRLLCKDNENSIIRCPDRKRCCVPSQYLTIQPITIDGIVDLSTAMMSAQAPTKKKKRNHG
    

Molecular Weight9858.76 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)4.53

Net Charge (pH 7.4) 4.16

Charge Density (pH 7.0) 0.0521

GRAVY Index-0.02

Hydrophobic Moment 0.59

Boman Index-0.01

Instability Index48.81

Aliphatic Index 91.95

Aromaticity 0.0460

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3879.22

LogP -34.42

H-bond Donors 140.0

H-bond Acceptors 138.0

Rotatable Bonds 334.0

Heavy Atoms 681.0

Ring Count 11.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407125 VERIFIED: NO

Provenance & Taxonomy

OrganismCastor canadensis [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin