Peptide Database

Peptide NameGrowth/differentiation factor 2

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length110 amino acids

Chemical FormulaC541H835N139O157S9

DescriptionStandard

        SAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGCR
    

Molecular Weight12086.84 Da

Isoelectric Point (pI)6.85

Net Charge (pH 7.0)-0.25

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0023

GRAVY Index-0.12

Hydrophobic Moment 0.53

Boman Index0.09

Instability Index37.97

Aliphatic Index 73.55

Aromaticity 0.1000

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4665.23

LogP -42.01

H-bond Donors 167.0

H-bond Acceptors 170.0

Rotatable Bonds 388.0

Heavy Atoms 846.0

Ring Count 24.0

Amide Bonds 112.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0243953 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-74; 37-107; 41-109

Bio-Activity Profile

Function

Cytokine Growth factor TGF-beta family Growth factor signaling Angiogenic