Peptide Database

Peptide NameCytotoxic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length466 amino acids

Chemical FormulaC2207H3431N611O698S16

DescriptionStandard

        MGTGYFLVRGDKTTCGGKIIEGADDHTIMGIPQARDMDRVTCGKHSGMFIIVGGVPETDIHGRLMAGSLDSQSSCPCKARFIASMMDDVYETGGGDSGEDDQDDSNNGKATGQNIPTIKKEFTPENDDPSVTPVFAKSCLRGSGCTDAGTESEPVDNFGEMSFYQAAAAAGTITHTGASESAGSTVLRLIGKAASRVLPGRLAVPNPVTVGVIGIFWSEGLNKGEEDYLNNIRLTQLATLQGTAPTRVRFQWVTNAITGKPEIRGYHTGSDGQISDQVPVRMLTPNVGHKDLYEFWESGAKGPSILWTPDNPGYAPPSDTGNDDVFVPPPSVLIYPLPTDTGSSTEILPMPEEKDFRDYILVHPTGDFDPIYVVLSSPHKYFTPPQTNPPLPAFPDAKKAPRKTVIQGGGGLRARWKDSKGKIYEWDSQHGTVEVYDKSGRRHLGEFDPATGKQTKPADPTRRVEK
    

Molecular Weight50204.57 Da

Isoelectric Point (pI)5.31

Net Charge (pH 7.0)-12.62

Net Charge (pH 7.4) -13.55

Charge Density (pH 7.0) -0.0271

GRAVY Index-0.51

Hydrophobic Moment 0.80

Boman Index-0.01

Instability Index42.79

Aliphatic Index 65.28

Aromaticity 0.0751

Extinction Coeff. Reduced 52370.00

Extinction Coeff. Oxidized 52745.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238840 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli M114 [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli

MethodQualitative functional evidence