Peptide Database

Peptide NameClosticin 574

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC390H625N101O104S2

DescriptionStandard

        PNWTKIGKCAGSIAWAIGSGLFGGAKLIKIKKYIAELGGLQKAAKLLVGATTWEEKLHAGGYALINLAAELTGVAGIQANCF
    

Molecular Weight8456.88 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)5.03

Net Charge (pH 7.4) 4.87

Charge Density (pH 7.0) 0.0613

GRAVY Index0.39

Hydrophobic Moment 0.55

Boman Index0.28

Instability Index3.62

Aliphatic Index 109.76

Aromaticity 0.0854

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3243.15

LogP -25.61

H-bond Donors 115.0

H-bond Acceptors 112.0

Rotatable Bonds 285.0

Heavy Atoms 597.0

Ring Count 12.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413748 VERIFIED: YES

Provenance & Taxonomy

OrganismClostridium tyrobutyricum [Bacterium]

FamilyBacteriocin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetClostridium beijerinckii ATCC 25752

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