MYP_040069
Corticoliberin
Antimicrobial
Antiparasitic
▸
Antiprotozoal
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Anti-Trypanosoma
Antiparasitic
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General antiparasitic
▸
Antiparasitic
Cardiovascular
Delivery / Targeting
▸
Barrier transport
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Blood-brain barrier shuttle
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Blood-Brain Barrier
Delivery / Targeting
▸
Drug delivery vehicle
Hormonal / Endocrine
▸
Hormone peptide
Immunology
▸
Inflammation modulation
▸
Anti-inflammatory
Neurological / Signaling
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Analgesic/opioid activity
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Analgesic
Neurological / Signaling
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Neuromodulation
Neurological / Signaling
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Neuropeptide activity
▸
Neuropeptide
Neurological / Signaling
▸
Neuropeptide activity
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Stress-related neuropeptide
Neurological / Signaling
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Pain modulation
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Pronociceptive activity
Neurological / Signaling
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Sleep regulation
Regulatory peptide
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Biological modulation
Regulatory peptide
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Biological regulation
Regulatory peptide
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Cell-cell communication
Reproductive biology
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Reproductive modulation
Standard
41 amino acids
C208H343N59O64S2
Standard
SEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII
4758.44 Da
5.09
-3.35
-3.67
-0.0817
-0.26
0.77
-0.03
52.47
111.95
0.0244
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1993.20
-16.71
67.0
65.0
163.0
333.0
5.0
44.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0197553
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
ACTH
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anti-edema
Anti-inflammatory
ELISA
Rat plasma (Subcutaneous), in vivo; 3756 s
RECORD: Rec_0200201
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Sauvagine/corticotropin-releasing factor/urotensin I
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
Stress-related neuropeptide
RECORD: Rec_0205603
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 80.5%, E 0.0%, T 2.4%, C 17.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiparasitic
Cell-Cell Communication
Antimicrobial
Drug Delivery Vehicle
Antitrypanosomal
Hormones
Blood-Brain Barrier
Neuropeptide
RECORD: Rec_0224795
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Hormone-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Antiparasitic
Antitrypanosomal
Trypanosoma brucei brucei AnTat 1.1 (blood stage form)
5.3±2.4 μM
LD50; MTT assay
RECORD: Rec_0224914
VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Corticoliberin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Analgesic
Pronociceptive
Hormone
Endocrine
Neuropeptide
Neuromodulator
Cardiovascular
Metabolic regulation
Physiological regulation
Reproductive regulator
Growth regulation
Development regulation
Receptor modulation
intestinal epithelial cells
Experimental: 30.5±3.3 minutes; /1830 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
Showing 5 records on this page · Page 3 of 5