Peptide Database

Peptide NameDermaseptin H2 protein

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC370H604N98O127S3

DescriptionStandard

        MDILKKSLFIVLFLGLVSLSICEEEKRENEDEEEQEDDEQSEEKRALWKSLLKNVGVAAGKAALNAVTDMVNQGEQ
    

Molecular Weight8553.53 Da

Isoelectric Point (pI)4.35

Net Charge (pH 7.0)-9.47

Net Charge (pH 7.4) -9.74

Charge Density (pH 7.0) -0.1247

GRAVY Index-0.46

Hydrophobic Moment 0.56

Boman Index-0.07

Instability Index60.38

Aliphatic Index 97.50

Aromaticity 0.0395

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3705.05

LogP -35.46

H-bond Donors 124.0

H-bond Acceptors 121.0

Rotatable Bonds 307.0

Heavy Atoms 598.0

Ring Count 4.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0132221 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa hypochondrialis [Animal]

FamilyDermaseptin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0392106 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyDermaseptin

Tax ID317381

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal