Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length541 amino acids

Chemical FormulaC2671H4237N763O736S20

DescriptionStandard

        MGDVPVQPAHPLQDGHWRHRSLLPAATHKESGPTMGPAAPVGHAARTCRCPGVSGSLPARVHLLSGATLGMWLCLLLLMAACVPTSTSSPGIKGRVTRSALEYGRRFGLDLLRSLLQKEHDVNLQGSYRAPFLGRLNYTVPQIHIHELQMNDSTVDFAEDVGVQLTVDRARIQLSATWRAQLGAWQDSGSLQLRIRDLAVAVLLGLGADEQGQPSMWAAGCDARGTDLRLEFHQGQSWLYNLLVPLLQRTLRQQLNKQLCVEIQKGIGRLQDSLKNVRVSAQLDAFAAIDLSLLGQPGITKQHGDVDLKGEFFGVRGQWQSPFSAQPVELPELQEPMLLVAVTEFVANTAAFVYFTAGALRRNITAEMLPRRFPLKLNTESMGNFAPQLQQHFPSRPVELHLWARRQPLLSCHPNALHGAFFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTIAGNRLGGTVGLKSLNVMQVMSYVGPLQVEKLENMLKFGLWLFGVPWANKRLHPGIPLPTPHGITLLHPRLSLHKGFMLITTDLQYKP
    

Molecular Weight59455.18 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)13.14

Net Charge (pH 7.4) 11.78

Charge Density (pH 7.0) 0.0243

GRAVY Index-0.05

Hydrophobic Moment 0.79

Boman Index0.08

Instability Index49.60

Aliphatic Index 97.73

Aromaticity 0.0702

Extinction Coeff. Reduced 65430.00

Extinction Coeff. Oxidized 65805.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0391971 VERIFIED: NO

Provenance & Taxonomy

OrganismMeleagris gallopavo [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria