Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length514 amino acids

Chemical FormulaC2556H4074N706O718S18

DescriptionStandard

        MALHATLTNSSLFGRDIKVVWAGRAQHCTALQEGRMGMQSVALACGALALCLALTTATNPGFVVRMTQAGLDYAHQQGISILEKELAQLRLPDISGETRVLHVGKVRYEFSRLRLRDFHLPHSRITPVSNMGLQVSISNAFAELDGDWRVKFLFIRDHGSFNLKVENIYMKIVLRLGSDTTGKPTISTSDCSARISKVRVLFSGKLGWLYNLFHSVIESKLRKSLERKVCDNVAKSVHNELQSYIRTLPVTARIDDKIGIDYSLVAPPRATAQSLDADLKGEFYSLAHRSPVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHKAGALVFEITEAMIPKESGLILDTSAFSAFIPQLEEMYPNMSMKFRLSTPTAPFLTIGPGGISFQPIVDAQAYAILPNSSLAPLFLLSLTGNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGHFQLRTMQSLMNILTSNALLPRLNARLDEGFPLPLLDRIQLSNILVRFHQNFLLLGADVRFQPRG
    

Molecular Weight56759.16 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)13.72

Net Charge (pH 7.4) 12.63

Charge Density (pH 7.0) 0.0267

GRAVY Index0.10

Hydrophobic Moment 0.68

Boman Index0.09

Instability Index36.16

Aliphatic Index 102.10

Aromaticity 0.0837

Extinction Coeff. Reduced 34380.00

Extinction Coeff. Oxidized 34630.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168159 VERIFIED: NO

Provenance & Taxonomy

OrganismTaeniopygia guttata [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence