Peptide Database

Peptide NameD-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Nal-NH2

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC43H62N10O10S2

DescriptionStandard

        ACYWKVCA
    

Molecular Weight943.14 Da

Isoelectric Point (pI)8.09

Net Charge (pH 7.0)0.77

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0968

GRAVY Index0.84

Hydrophobic Moment 0.18

Boman Index0.31

Instability Index40.10

Aliphatic Index 61.25

Aromaticity 0.2500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 329.06

LogP -0.85

H-bond Donors 14.0

H-bond Acceptors 13.0

Rotatable Bonds 26.0

Heavy Atoms 65.0

Ring Count 3.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0256526 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetBB1 receptor (Human); BB1 receptor (Rat); BB2 receptor (Human)

Activity275-605 nM

MethodIC50