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MYP_039983
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Basic Information
Guanylate-binding protein 1 (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (mGBP-1) (mGBP1) (Guanine nucleotide-binding protein 1) (Interferon-gamma-inducible protein MAG-1) (Interferon-induced guanylate-binding protein 1)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Enzyme / Catalytic activity ▸ Hydrolase
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
589 amino acids
C2998H4774N798O916S33
Standard
Sequence
MASEIHMSEPMCLIENTEAQLVINQEALRILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKRTGFSLGSTVQSHTKGIWMWCVPHPKKAGQTLVLLDTEGLEDVEKGDNQNDCWIFALAVLLSSTFIYNSIGTINQQAMDQLHYVTELTDLIKSKSSPDQSDVDNSANFVGFFPIFVWTLRDFSLDLEFDGESITPDEYLETSLALRKGTDENTKKFNMPRLCIRKFFPKRKCFIFDRPGDRKQLSKLEWIQEDQLNKEFVEQVAEFTSYIFSYSGVKTLSGGITVNGPRLKSLVQTYVSAICSGELPCMENAVLTLAQIENSAAVQKAITYYEEQMNQKIHMPTETLQELLDLHRTCEREAIEVFMKNSFKDVDQKFQEELGAQLEAKRDAFVKKNMDMSSAHCSDLLEGLFAHLEEEVKQGTFYKPGGYYLFLQRKQELEKKYIQTPGKGLQAEVMLRKYFESKEDLADTLLKMDQSLTEKEKQIEMERIKAEAAEAANRALAEMQKKHEMLMEQKEQSYQEHMKQLTEKMEQERKELMAEQQRIISLKLQEQERLLKQGFQNESLQLRQEIEKIKNMPPPRSCTIL
Physicochemical Analysis
67710.92 Da
5.41
-14.59
-15.68
-0.0248
-0.46
0.63
-0.06
46.61
83.29
0.0798
51340.00
51965.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0099168 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Mycobacterium bovis (Gram-positive)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID1753106;1715024;15489334;10888661;18025219;21183079;21551061 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1753106/
RECORD: Rec_0115229 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Toxoplasma gondii
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID1753106;1715024;15489334;10888661;18025219;21183079;21551061 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1753106/
RECORD: Rec_0118550 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Listeria monocytogenes (Gram-positive)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID1753106;1715024;15489334;10888661;18025219;21183079;21551061 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1753106/
RECORD: Rec_0215035 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ7542