Peptide Database

Peptide NameType VI secretion system tip protein VgrG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Standard StatusStandard

Sequence Length1198 amino acids

Chemical FormulaC5851H9138N1676O1799S32

DescriptionStandard

        MDNWSALFDGQTRYVLDINDSTVKADVLRFRGREALSEPFRWDIEFTSLHANIPPEQVLMKYASLRMRGGKNVHGVVTRLEWLSTSRDQSHYRLTLSSRLTLLGYTRQCAVFQNLSVPEVVEQVLRKHGLEGPDFEFRLERTYPARELITQWRETDLQFIQRILSEVGIYWRTEMDDVHGLDTCILADSQLNYRFDVQLPYSEPSGLFDGAADSVWDVRTWHNIATGTVATRDYNYRTATMPMDATVSVRSDAVTTGAHYRYTAPYRDAGDDTSPELETESGAFYARIHHERELSRSARIHLFSNTGHLTPGQVLEPQGDVITALKEGVILTLVTFRGARDSRLHVSVWGVPYTERYCFRPAEIPRPLIPGTLPARIESREKNDIYAHLDEQGRYRVRLDFDRDATAPGYGYLWLRMAKPTAGETSGWHTPLTDGTEVAIAYSNGDIDLPYIACALHDSEHPDHVTRDNHTRNVLRTPANNKLRMEDRRGEEHIKLATEYGKSQLNSGHLVDSKGQRRGTGAELRTDEHGVIRAGKGLFVSADAQPKAQGEALDRDAALKEIDRLNQQLQQLEIAAEKAQALKADVDSQIQMFAQRLKPLNEALLMTAPEGMALTSGEDMQLAAGRNLAVNAGGDISVGTMGNLTALAGEKLGLFAHTGQLSLKSGEGAIDVQAQNASLRLFAEKKLRLSSASDISFAGKKRITLIGGGSYLRLEAGKVEYGTTASYMRKVKRTMAASASAKPAEAVSLPPPATMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAEEPVDNFGQMTIFAQPVEDDCCGYGHQHEHADDEVVQHAQSAKKRKPDAGGANAPAPAQATAAPLALGAATGVMTQVWGEWSLTGVLGAARGIPYVGAMMSALYVPSAGEGSDRVPGRDEFWYEEELRQKALTGAKATTRVRFFWRQDEQGNMRVYGVHTGEGTPYEGVRTANMVWNSENNRYEFTPAHGADGPLITWTPERPEGSDLPSHTGSDIRPIDQATILVTPIPDGKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKDDARNVPGEATGNGVKLSGDKPWLDMSVTNSGEGAPIPSQIADKLRGQKFNSFDDFRETIWNEIGRHPELTKDFTTVNKDRIEDGLAPWVPKEGQYIGPNSIVKKFAIHHVVPIKDGGGVYDMDNLRIVTPKLHDEIHYRR
    

Molecular Weight132769.38 Da

Isoelectric Point (pI)5.71

Net Charge (pH 7.0)-25.39

Net Charge (pH 7.4) -27.77

Charge Density (pH 7.0) -0.0212

GRAVY Index-0.50

Hydrophobic Moment 0.74

Boman Index-0.05

Instability Index32.92

Aliphatic Index 76.18

Aromaticity 0.0793

Extinction Coeff. Reduced 171090.00

Extinction Coeff. Oxidized 171590.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0187637 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella diarizonae [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase

TargetEscherichia coli