Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length120 amino acids

Chemical FormulaC619H963N165O178S7

DescriptionStandard

        FQSLYICFVFVFLPLSFAYRGGKRCWHKRGHCRKVCKADEVVKSTCKKHQACCVSVKKDNKQEAINKKIPITTPSNFIEYYVTVFPTTVKFDIDITNKEDENYATEVGTLTPNTEVHQSS
    

Molecular Weight13788.72 Da

Isoelectric Point (pI)8.97

Net Charge (pH 7.0)6.05

Net Charge (pH 7.4) 5.49

Charge Density (pH 7.0) 0.0504

GRAVY Index-0.39

Hydrophobic Moment 0.72

Boman Index-0.05

Instability Index49.13

Aliphatic Index 68.92

Aromaticity 0.1167

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5568.45

LogP -53.86

H-bond Donors 199.0

H-bond Acceptors 195.0

Rotatable Bonds 456.0

Heavy Atoms 969.0

Ring Count 24.0

Amide Bonds 129.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0221128 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence