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MYP_039909
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Basic Information
Z4
Antimicrobial
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Standard
13 amino acids
C78H152N34O14
Standard
Sequence
IRIIRRRRRIIRI
Physicochemical Analysis
1790.26 Da
12.00
6.76
6.56
0.5200
-0.35
0.95
-0.73
185.48
180.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
845.82
-5.66
35.0
21.0
65.0
126.0
0.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0049133 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
Klebsiella pneumoniae CMCC46117
32 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0065213 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
P-aeruginosa ATCC 9027
>64 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0093856 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
3 strains A-baumannii SYP-B4290/B4291/B3819
>64 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0118589 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
4 strains E-coli ATCC 9637 or SYP-B3820/B4288/B4289
>64 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0337103 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
S-paratyphi ATCC 14028
>64 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.