Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length443 amino acids

Chemical FormulaC2208H3502N572O637S13

DescriptionStandard

        MELVKQAVLKETFPSWSGQESLSVVKVNYVISRLRINAVDFPETSASFIPGTGICLSVARASATISADWRMNAWLLKGKGEITVSISGLFISIIFNVSRDSTGHLSTLLHNCQLSIGSVKVKLSGRSSWIYSFLSGYLEKPIHTKLDKNLCLNIKYKIQMMDAQLKKHKVLSQIDTFAQVDYSLLSSPAVFKSHINLDLKGTVYPVGNHTDPPFMPAPFALPNQGDSMIYLGVSNYFLKSASLAYYRAGAFNITISEELATTFSLNTSLLKYFVSETSLSQAAACPVLLNLMATLPPAVSLNADRCVLQITGSVEVFAALPNSTTQYIFTGNLTASTTANLTITKQKLIISLLLKRFQFSLLHSNLGFPEQKSVVENFLSYALRRVVIPVINDKLGKGFPLLNLAHTSLTGPAIKMNQGHLVISTDVHYQPVDREDEDLHSHS
    

Molecular Weight48669.72 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)8.51

Net Charge (pH 7.4) 7.52

Charge Density (pH 7.0) 0.0192

GRAVY Index0.15

Hydrophobic Moment 0.63

Boman Index0.15

Instability Index32.65

Aliphatic Index 104.54

Aromaticity 0.0880

Extinction Coeff. Reduced 42860.00

Extinction Coeff. Oxidized 43110.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072788 VERIFIED: NO

Provenance & Taxonomy

OrganismLepidothrix coronata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria