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MYP_039877
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Basic Information
KF4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Lactocepin Inhibitor
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
2 amino acids
C11H20N2O3
Standard
Sequence
LP
Physicochemical Analysis
228.29 Da
5.53
-0.24
-0.44
-0.1200
1.10
0.52
0.59
101.30
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
83.63
0.44
2.0
3.0
4.0
16.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019925 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide topology [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella Typhimurium
PMID28512456 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28512456/
RECORD: Rec_0041539 VERIFIED: YES
Provenance & Taxonomy
marine natural metabolite [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
Lactam
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-468
67.4 μM
IC50
PaperPubMed PMID: 31669320 PMID31669320 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31669320/
RECORD: Rec_0075471 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Soy-derived peptide
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Sour
PaperTwo-stage selective enzymatic hydrolysis generates protein hydrolysates rich in Asn-Pro and Ala-His for enhancing taste attributes of soy sauce. Food Chem., 345, 128803, 2021 PMID33310561 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33310561/
RECORD: Rec_0119373 VERIFIED: YES
Provenance & Taxonomy
marine natural metabolite [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
Lactam
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MCF-12A
100 μM
IC50
PaperPubMed PMID: 31669320 PMID31669320 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31669320/
RECORD: Rec_0126593 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV Inhibitory
Dipeptidyl peptidase IV
2370.0
IC50
PaperHatanaka T., Inoue Y., Arima J., Kumagai Y., Usuki H., Kawakami K., Kimura M., Mukaihara T.. Production of dipeptidyl peptidase IV inhibitory peptides from defatted rice bran. Food Chem., 134, 797-802, 2012.
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