Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC413H633N111O117S10

DescriptionStandard

        MKLLFLFLAILLATEPVMPGKSLRCMATIGTCRHSCKKNEHPYYHCRDYQTCCLPSFMRISITGTDENNEWSDGNYWPQAP
    

Molecular Weight9345.77 Da

Isoelectric Point (pI)7.61

Net Charge (pH 7.0)0.71

Net Charge (pH 7.4) 0.23

Charge Density (pH 7.0) 0.0088

GRAVY Index-0.30

Hydrophobic Moment 0.51

Boman Index0.02

Instability Index42.43

Aliphatic Index 66.30

Aromaticity 0.1111

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3630.97

LogP -32.78

H-bond Donors 131.0

H-bond Acceptors 131.0

Rotatable Bonds 297.0

Heavy Atoms 651.0

Ring Count 20.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177471 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0223060 VERIFIED: NO