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MYP_039850
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Basic Information
Amphiphatic peptide CT2 (VmCT2; Non-disulfide-bridged peptide 5.14, NDBP-5.14; Arthropods, animal
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C73H108N16O18
Standard
Sequence
FLSTLWNAAKSIF
Physicochemical Analysis
1497.73 Da
8.75
0.76
0.55
0.0584
0.82
0.52
0.40
36.94
105.38
0.2308
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
558.11
-3.03
20.0
19.0
46.0
107.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002524 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
20 μM
MIC
PMID22342498 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22342498/
RECORD: Rec_0058248 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
10 μM
MIC
PMID22342498 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22342498/
RECORD: Rec_0075729 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
10 μM
MIC
PMID22342498 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22342498/
RECORD: Rec_0082506 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis ATCC 6633
20 μM
MIC
PaperGene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae.
RECORD: Rec_0089360 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 61.5%, E 0.0%, T 7.7%, C 30.8% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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