Peptide Database

Peptide NameBW443 (Enkephalin Analogue)

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC30H41N9O8

DescriptionStandard

        YRGFN
    

Molecular Weight655.70 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.1518

GRAVY Index-1.38

Hydrophobic Moment 0.84

Boman Index-0.28

Instability Index-42.80

Aliphatic Index 0.00

Aromaticity 0.4000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 304.94

LogP -2.70

H-bond Donors 11.0

H-bond Acceptors 9.0

Rotatable Bonds 19.0

Heavy Atoms 47.0

Ring Count 2.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0048626 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyEnkephalin

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermAmidation

Other Mods4 nitro groups linked to Phenylalanine (phe) at 4th position

Bio-Activity Profile

Function

Analgesic

MethodRadioimmunoassay

Half-LifeHuman plasma, in vivo; 7200 s