Peptide Database

Peptide NameCorticotropin-like intermediary peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC258H401N63O95S2

DescriptionStandard

        PVKVYPNGVEEESAEAYPTEMRRDLMSDLDYPLLEEVEEELGGENEVLNLQE
    

Molecular Weight5969.44 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-13.00

Net Charge (pH 7.4) -13.09

Charge Density (pH 7.0) -0.2500

GRAVY Index-0.80

Hydrophobic Moment 0.49

Boman Index-0.09

Instability Index81.77

Aliphatic Index 84.23

Aromaticity 0.0577

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2547.42

LogP -22.47

H-bond Donors 83.0

H-bond Acceptors 84.0

Rotatable Bonds 200.0

Heavy Atoms 418.0

Ring Count 7.0

Amide Bonds 55.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0256336 VERIFIED: NO

Provenance & Taxonomy

OrganismLepisosteus osseus [Animal]

FamilyPOMC

Tax ID34771

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0264467 VERIFIED: YES

Provenance & Taxonomy

OrganismLepisosteus osseus [Animal]

FamilyCorticotropin-like intermediary peptide

Tax ID34771

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: >20 hour; Yeast: >20 hour; E. coli: ?

RECORD: Rec_0297783 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/