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MYP_039774
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Basic Information
DSIP (Delta sleep inducing peptide)
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
9 amino acids
C35H48N10O15
Standard
Sequence
WAGGDASGE
Physicochemical Analysis
848.81 Da
4.09
-2.23
-2.44
-0.2479
-0.70
0.10
0.19
-2.48
22.22
0.1111
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
406.74
-5.73
14.0
13.0
25.0
60.0
2.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006925 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Stress reliever stimulates LH somatostatin
Radioimmunoassay
Mongrel dog plasma(Dose i/v injected), in vivo; 434.4 s
PMID3768731 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3768731/
RECORD: Rec_0055986 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Neuropeptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
Neuropeptide
Mongrel dog plasma after i.v. injection
Radioimmunoassay
7.24 ± 0.77 min
PaperEntry of DSIP peptides into dog CSF: role of physicochemical and pharmacokinetic parameters
RECORD: Rec_0061827 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0177403 VERIFIED: NO
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
9986
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Behavior Regulator
RECORD: Rec_0182683 VERIFIED: YES
Provenance & Taxonomy
Unknown [Animal]
Delta sleep-inducing peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Experimental: 7.24±0.77 minutes; /434.4 seconds; Mammalian: 2.8 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Delta sleep-inducing peptide: PMID 21262293##3768731 PMID21262293;3768731 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21262293/
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