Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length162 amino acids

Chemical FormulaC828H1326N232O239S5

DescriptionStandard

        MPMPEEKDFRDYILIFPIPNMPPVYVYLSKPPVKLFEVDLYRNFAGRLRNGTHADHMPSAAAVKKRLKRLNSKLTDAQLNQLSKDVAAIIIPAEIHQKLSATYGGRNSPIQIGQDEKDLKAAVNRDFNAIKPALKNYGATEEQLEKAQEKMHEINQKQRLYE
    

Molecular Weight18515.12 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)4.87

Net Charge (pH 7.4) 4.39

Charge Density (pH 7.0) 0.0301

GRAVY Index-0.63

Hydrophobic Moment 0.67

Boman Index-0.11

Instability Index46.98

Aliphatic Index 85.00

Aromaticity 0.0741

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7639.70

LogP -71.58

H-bond Donors 254.0

H-bond Acceptors 253.0

Rotatable Bonds 625.0

Heavy Atoms 1304.0

Ring Count 28.0

Amide Bonds 180.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0328573 VERIFIED: NO

Provenance & Taxonomy

OrganismPhotorhabdus temperata subsp. temperata Meg1 [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli

MethodQualitative functional evidence