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MYP_039709
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Basic Information
VP (Vasopressin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
9 amino acids
C46H66N14O13S2
Standard
Sequence
CYFQNCPRG
Physicochemical Analysis
1087.23 Da
8.06
0.74
0.51
0.0821
-0.78
0.52
-0.17
9.28
0.00
0.2222
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
455.64
-5.13
17.0
16.0
31.0
75.0
3.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0034107 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Vasopressin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
1-6
Bio-Activity Profile
Anti-diuretic
Radioimmunoassay, HPLC
(Dose i/v injected)urine of women with endometriosis, in vivo; 4800 s
PMID2521208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2521208/
RECORD: Rec_0038118 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Vasopressin/Oxytocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Neuropeptide
PaperHruby V. J., Chow M., Smith D. D.. Conformational and structural considerations in oxitocin-receptor binding and biological activity. Annu. Rev. Pharmacol. Toxicol., 30, 501-534 (1990).
RECORD: Rec_0047146 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]; Homo sapiens [Animal]; Mus musculus [Animal]; Rattus norvegicus [Animal]
Neurohypophyseal peptide
9913; 9606; 10090; 10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
1-6
Bio-Activity Profile
Hormonal Anti-diuretic
Urine of women with endometriosis after i.v. injection
Radioimmunoassay, HPLC
80 min
PaperPharmacokinetics of vasopressin and atrial natriuretic peptide in anesthetized rabbits
RECORD: Rec_0059111 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Arg-vasopressin
9940
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Metabolic regulation Physiological regulation Receptor modulation
vasopressin receptors
Experimental: 1.06±0.19 (fast phase) minutes; /63.6 seconds; Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Arg-vasopressin (Ovis aries): PMID 17258819 PMID17258819 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17258819/
RECORD: Rec_0059318 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Vasopressin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Anti-diuretic Vasopressor
10-20 min
PaperPubMed-linked source references: PMID:17122081; PMID:17083331; PMID:15555506; PMID:14647484; PMID:7545469 PMID17122081;17083331;15555506;14647484;7545469 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17122081/
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