Peptide Database

Peptide NameMacrophage migration inhibitory factor

Function Ontology

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC548H853N151O164S6

DescriptionStandard

        PMFIVNTNVPRASVPEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTNDPCALCSLHSIGKIGGAQNRNYSKLLCGLLSDRLHISPDRVYINYYDMNAANVGWNGSTFA
    

Molecular Weight12372.94 Da

Isoelectric Point (pI)7.28

Net Charge (pH 7.0)0.19

Net Charge (pH 7.4) -0.08

Charge Density (pH 7.0) 0.0017

GRAVY Index-0.04

Hydrophobic Moment 0.57

Boman Index0.12

Instability Index20.01

Aliphatic Index 87.28

Aromaticity 0.0877

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5024.43

LogP -54.83

H-bond Donors 173.0

H-bond Acceptors 173.0

Rotatable Bonds 396.0

Heavy Atoms 869.0

Ring Count 21.0

Amide Bonds 128.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0425598 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyMIF family

Tax ID10090; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other Mods77-Lys: N6-acetyllysine; alternate; 77-Lys: N6-succinyllysine; alternate

Bio-Activity Profile

Function

Cytokine Growth factor MIF family Chemoattractant Chemokine-like