‹ ›
MYP_039571
← PREVIOUS NEXT → BACK
Basic Information
NoD173
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
47 amino acids
C222H377N75O63S8
Standard
Sequence
RQCKAESNTFTGICIAKPPCRQACIREKFTDGHCSKVLRRCLCTKRC
Physicochemical Analysis
5361.35 Da
9.45
7.77
7.39
0.1653
-0.49
0.62
-0.29
60.37
54.04
0.0426
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2277.07
-27.85
90.0
80.0
182.0
368.0
5.0
49.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0210012 VERIFIED: YES
Provenance & Taxonomy
Nicotiana occidentalis [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
1.35±0.06 μM
IC50
PaperPubMed PMID: 30794440 PMID30794440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30794440/
RECORD: Rec_0221126 VERIFIED: YES
Provenance & Taxonomy
Nicotiana occidentalis [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
PC-3
6.31±0.099 μM
IC50
PaperPubMed PMID: 30794440 PMID30794440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30794440/
RECORD: Rec_0309866 VERIFIED: YES
Provenance & Taxonomy
Nicotiana occidentalis [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MM170
1.75±0.06 μM
IC50
PaperPubMed PMID: 30794440 PMID30794440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30794440/
RECORD: Rec_0331136 VERIFIED: YES
Provenance & Taxonomy
Nicotiana occidentalis [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human red blood cells: with ∼12% lysis at the very high concentration (100 μM)
PaperPubMed PMID: 30794440 PMID30794440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30794440/
RECORD: Rec_0419165 VERIFIED: YES
Provenance & Taxonomy
Nicotiana occidentalis [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 30794440 PMID30794440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30794440/