Peptide Database

Peptide NameMERS-CoV-HR2P [T1263E,L1267R]

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC186H308N46O62S

DescriptionStandard

        SLTQINTTLLDLEYEMRSLQQVVKALNESYIDLKEL
    

Molecular Weight4212.77 Da

Isoelectric Point (pI)4.36

Net Charge (pH 7.0)-3.53

Net Charge (pH 7.4) -3.75

Charge Density (pH 7.0) -0.0981

GRAVY Index-0.18

Hydrophobic Moment 0.78

Boman Index0.00

Instability Index27.79

Aliphatic Index 127.22

Aromaticity 0.0556

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1796.85

LogP -15.59

H-bond Donors 61.0

H-bond Acceptors 60.0

Rotatable Bonds 147.0

Heavy Atoms 295.0

Ring Count 2.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419743 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetMERS-CoV

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