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MYP_039509
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Basic Information
IK8 “D isoform ”, D-IK8
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
8 amino acids
C48H94N16O9
Standard
Sequence
IRIKIRIK
Physicochemical Analysis
1039.36 Da
12.00
3.76
3.55
0.4698
0.15
0.39
-0.32
-23.09
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
442.86
-1.24
17.0
13.0
39.0
73.0
0.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0078370 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus pseudintermedius MSSP
4 μM
MIC50
PMID25551573;27405275;24211081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25551573/
RECORD: Rec_0079788 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli(MIC>500 mg/L)
PMID24211081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24211081/
RECORD: Rec_0083972 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
3.9 μg/mL
MIC
PMID24211081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24211081/
RECORD: Rec_0139136 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
62.5 μg/mL
MIC
PMID24211081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24211081/
RECORD: Rec_0194935 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Hemolytic
mouse red blood cells
774 μM
Hemolysis
PMID25551573;27405275;24211081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25551573/
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