Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC342H573N95O95S

DescriptionStandard

        MARLWVNPTPPASLAAVVLNVVQAGGAITTIVSILTAIGSGGLSLLAAAGKETIRQYLNQQIKEKGRKAVIAW
    

Molecular Weight7567.85 Da

Isoelectric Point (pI)10.55

Net Charge (pH 7.0)4.50

Net Charge (pH 7.4) 4.27

Charge Density (pH 7.0) 0.0617

GRAVY Index0.50

Hydrophobic Moment 0.59

Boman Index0.24

Instability Index21.93

Aliphatic Index 124.38

Aromaticity 0.0411

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3032.04

LogP -28.49

H-bond Donors 105.0

H-bond Acceptors 101.0

Rotatable Bonds 249.0

Heavy Atoms 533.0

Ring Count 8.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267408 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus larvae subsp. pulvifaciens [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal