Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC452H726N132O134S8

DescriptionStandard

        MRTLIILAVILLVALQAQAGPLQERADEAAVAKEEISANNNEVAISFAWDESLIRRDSGSRENMACFCRIPSCIAGERRLGTCFYQGRVWAFCC
    

Molecular Weight10409.92 Da

Isoelectric Point (pI)5.36

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.86

Charge Density (pH 7.0) -0.0163

GRAVY Index0.18

Hydrophobic Moment 0.53

Boman Index0.06

Instability Index56.48

Aliphatic Index 96.70

Aromaticity 0.0745

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4303.83

LogP -42.48

H-bond Donors 157.0

H-bond Acceptors 141.0

Rotatable Bonds 346.0

Heavy Atoms 726.0

Ring Count 11.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0003437 VERIFIED: NO

Provenance & Taxonomy

OrganismSaimiri boliviensis boliviensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0389240 VERIFIED: NO