Peptide Database

Peptide NameCasein alpha-s2 [089-098]

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC68H92N14O17

DescriptionStandard

        YQKFPQYLQY
    

Molecular Weight1377.54 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0756

GRAVY Index-1.33

Hydrophobic Moment 0.49

Boman Index-0.09

Instability Index65.04

Aliphatic Index 39.00

Aromaticity 0.4000

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 532.41

LogP -1.67

H-bond Donors 17.0

H-bond Acceptors 18.0

Rotatable Bonds 41.0

Heavy Atoms 99.0

Ring Count 5.0

Amide Bonds 12.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0312965 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyCasein-derived peptide

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity11.1 μM

MethodIC50

RECORD: Rec_0417002 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Familyalpha-S2-Casein-derived