Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length177 amino acids

Chemical FormulaC854H1354N250O250S11

DescriptionStandard

        MSAKIKYGLSAAVLALIAAGASAPQILDQFLDEKEGNHTTAYRDGSGIWTICRGATMVDGKPVFPGMKLSKEKCDQVNAIERDKALAWVEKNIKVPLSEPQKAGIASFCPYNIGPGKCFPSTFYKRINAGDRRGACEAIRWWIKDGGRDCRIRSNNCYGQVSRRDQESALACWGIDR
    

Molecular Weight19476.13 Da

Isoelectric Point (pI)9.14

Net Charge (pH 7.0)7.52

Net Charge (pH 7.4) 7.09

Charge Density (pH 7.0) 0.0425

GRAVY Index-0.39

Hydrophobic Moment 0.72

Boman Index-0.05

Instability Index44.40

Aliphatic Index 73.45

Aromaticity 0.0847

Extinction Coeff. Reduced 34950.00

Extinction Coeff. Oxidized 35450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8084.91

LogP -87.12

H-bond Donors 290.0

H-bond Acceptors 270.0

Rotatable Bonds 649.0

Heavy Atoms 1365.0

Ring Count 29.0

Amide Bonds 189.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028794 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli 2-460-02_S1_C1 [Bacterium]

FamilyLysozyme

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase

RECORD: Rec_0068894 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli O44:H18 [Bacterium]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0378066 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyLysozyme

Tax ID585034

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence