Peptide Database

Peptide NamePhakellistatin 13

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC42H56N8O9

DescriptionStandard

        PWLTPGF
    

Molecular Weight816.94 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0059

GRAVY Index0.20

Hydrophobic Moment 0.27

Boman Index0.53

Instability Index22.09

Aliphatic Index 55.71

Aromaticity 0.2857

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 251.16

LogP 0.26

H-bond Donors 9.0

H-bond Acceptors 9.0

Rotatable Bonds 19.0

Heavy Atoms 59.0

Ring Count 5.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0242818 VERIFIED: YES

Provenance & Taxonomy

OrganismPhakellia fusca [Animal]

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin Cytotoxic Anticancer

Targethuman hepatoma BEL-7404 cell line, BEL-7404 cell line

Activity0.01 μg/mL

MethodED50

RECORD: Rec_0410212 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Familyphakellistatin

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Anticancer