Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length507 amino acids

Chemical FormulaC2583H4017N637O741S18

DescriptionStandard

        MYTKMTPVLWGCLLLWNLYILSSQTIYPGIKARVTQRALDYGVQAGMEMIEQMVKEKKIPDLNGSESLEFLKVDYVNYNFSNIKINAFSFPNTSLAFVPGVGIKVLTNHGTANISTDWKIKSPLFQDTGGADLFLSGVFFTGIVILTRNDFGHPTLKLQDCYAQVSHAHVSFSGELSVLYNSFAEPMEKPILKNVNEMLCPTIIGEVEALNANLSTLEVLTKIDNYTLLDYSLISSPEITENYLDLNLKGVFYPLENLADPPFSPIPFVLPERSDSMLYIGISEYFFKSASLAYFTAGAFNVTLSTKEISNHFVQNSQGLGNVISRIAEIYILSQPFMVRVMAMEPPVINLQPGNFTLDIPASIMMLTQPKNSTVETIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLSLPESNRSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPHKVSFVSSDIEVLEGFLLISTDLKYETPSKQQPTFHGWEGLNLINGWWKGKPAP
    

Molecular Weight56427.52 Da

Isoelectric Point (pI)5.39

Net Charge (pH 7.0)-9.79

Net Charge (pH 7.4) -10.58

Charge Density (pH 7.0) -0.0193

GRAVY Index0.13

Hydrophobic Moment 0.68

Boman Index0.18

Instability Index37.72

Aliphatic Index 102.25

Aromaticity 0.1045

Extinction Coeff. Reduced 58330.00

Extinction Coeff. Oxidized 58580.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126050 VERIFIED: NO

Provenance & Taxonomy

OrganismCarlito syrichta [Animal]

FamilyBPI/LBP

Tax ID1868482

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria