Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC282H447N73O76S8

DescriptionStandard

        MKILLSLLGVLALLSIVPQARSLFQEGCPPGYYNCRMKCNVNEYAVRYCADWTICC
    

Molecular Weight6332.53 Da

Isoelectric Point (pI)8.27

Net Charge (pH 7.0)1.44

Net Charge (pH 7.4) 1.13

Charge Density (pH 7.0) 0.0257

GRAVY Index0.45

Hydrophobic Moment 0.50

Boman Index0.17

Instability Index34.13

Aliphatic Index 104.46

Aromaticity 0.1071

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2380.17

LogP -17.70

H-bond Donors 88.0

H-bond Acceptors 86.0

Rotatable Bonds 202.0

Heavy Atoms 439.0

Ring Count 10.0

Amide Bonds 60.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232331 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence