Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC428H671N119O124S11

DescriptionStandard

        MKAFSIAVAVTLVLAFVCILESSAVPFPGVQELEEAGSNDTPAAAHQETSMEPWTVPSHIRQKRQSHISLCRWCCNCCKANKGCGFCCKF
    

Molecular Weight9820.34 Da

Isoelectric Point (pI)7.53

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0076

GRAVY Index0.14

Hydrophobic Moment 0.57

Boman Index0.11

Instability Index63.93

Aliphatic Index 72.67

Aromaticity 0.0778

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3848.18

LogP -40.51

H-bond Donors 140.0

H-bond Acceptors 139.0

Rotatable Bonds 316.0

Heavy Atoms 682.0

Ring Count 17.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0208508 VERIFIED: NO

Provenance & Taxonomy

OrganismPsetta maxima [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0411148 VERIFIED: YES

Provenance & Taxonomy

OrganismScophthalmus maximus [Animal]

FamilyHepcidin

Tax ID52904

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal