Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC738H1164N206O216S5

DescriptionStandard

        METQRASLSLGRWSLWLLLLGLVVPSASAQALSYREAVLRAVDQLNELSSEANLYRLLELDPPPKDNEDLGTRKPVSFTVKETVCPRTIQQPAEQCDFKEKGRVKQCVGTVTLDPSNDQFDLNCNELQSVILPWKWRWWPWRRG
    

Molecular Weight16538.71 Da

Isoelectric Point (pI)6.31

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.82

Charge Density (pH 7.0) -0.0036

GRAVY Index-0.44

Hydrophobic Moment 0.66

Boman Index-0.07

Instability Index43.09

Aliphatic Index 90.00

Aromaticity 0.0833

Extinction Coeff. Reduced 41480.00

Extinction Coeff. Oxidized 41730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6832.64

LogP -63.36

H-bond Donors 239.0

H-bond Acceptors 221.0

Rotatable Bonds 540.0

Heavy Atoms 1165.0

Ring Count 29.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232843 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence