Peptide Database

Peptide NameSB1

Function Ontology

Antimicrobial

Antiviral

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC104H181N35O27S2

DescriptionStandard

        GSKKPVPIIYCNRRTGKCQRI
    

Molecular Weight2417.90 Da

Isoelectric Point (pI)10.47

Net Charge (pH 7.0)5.74

Net Charge (pH 7.4) 5.50

Charge Density (pH 7.0) 0.2732

GRAVY Index-0.78

Hydrophobic Moment 0.49

Boman Index-0.32

Instability Index39.88

Aliphatic Index 69.52

Aromaticity 0.0476

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1038.37

LogP -11.34

H-bond Donors 39.0

H-bond Acceptors 35.0

Rotatable Bonds 81.0

Heavy Atoms 168.0

Ring Count 3.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141482 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyThanatin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide11-18

Other ModsAPD analysis reveals that this sequence is poorly similar (95.24%) to Thanatin . Chemical modification: one disulfide bond C11-C18

Bio-Activity Profile

Function

Antimicrobial Antiviral

Targeted Human Immunodeficiency Virus Type 1 HIV-1IIIB

Activity13.1 μg/mL

MethodEC50