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MYP_039019
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
40 amino acids
C176H290N60O54S6
Standard
Sequence
AACSDRAHGHICESFKSFCKDSGRNGVKLRANCKKTCGLC
Physicochemical Analysis
4302.95 Da
9.13
4.91
4.52
0.1228
-0.46
0.63
-0.19
31.57
46.50
0.0500
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1870.61
-25.95
73.0
67.0
148.0
296.0
4.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0158396 VERIFIED: YES
Provenance & Taxonomy
Aurelia aurita [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes
PMID16890198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16890198/
RECORD: Rec_0206999 VERIFIED: YES
Provenance & Taxonomy
Aurelia aurita [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli strain ML-35p
7.66 μg/mL
MIC
PaperAurelin, a novel antimicrobial peptide from jellyfish Aurelia aurita with structural features of defensins and channel-blocking toxins
RECORD: Rec_0220393 VERIFIED: YES
Provenance & Taxonomy
Aurelia aurita [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
3-33, 12-37, 19-40
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes EGD
22.64 μg/mL
MIC
PMID16890198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16890198/
RECORD: Rec_0244894 VERIFIED: YES
Provenance & Taxonomy
Aurelia aurita [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0247446 VERIFIED: YES
Provenance & Taxonomy
Aurelia aurita [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Listeria monocytogenes strain EGD
22.64 μg/mL
MIC
PaperAurelin, a novel antimicrobial peptide from jellyfish Aurelia aurita with structural features of defensins and channel-blocking toxins
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